CHAPTER XVIII (b). By S. L. Jepson, M. D. EPIDEMICS The first epidemic of which we get any definite information was that of a disease called the "cold plague," which scourged the western settlements in 1820-21. The cases were marked by a sudden chill and great pulmonary congestion. Deaths were numerous. At that period swamps and ponds were numerous in and near Wheeling, and were a source of malarial fevers, diarrhoea and dysentery. During 1832-33 the first epidemic of Asiatic cholera visited Wheeling and neighborhood. The town was in extremely bad sanitary condition, and the advice of physicians being unheeded by the authorities, a great many cases occurred, with a mortality estimated at 50 to 60 per cent. The disease prevailed from May until late in July. In the spring of 1834 there occurred an outbreak of puerperal fever, which was extensive and very fatal. In connection with this, many cases of erysipelas(1) were also seen. Profuse bleeding, calomel and tarter emetic were the remedies most frequently used, and we may well pause to inquire whether more harm than good was not done by this treatment. In the winter of 1836 and 1837 occurred a very malignant epidemic of scarlet fever. Death often occurred in the forming stage of the disease. An individual would often be attacked in the evening with nausea and great prostration, and become comatose and die before morning, without any external development of the disease. The following winter (1836-7) scarlatina again prevailed with ever increased malignancy. Whole families were often stricken down with it, even in the country, on the hill-tops where the best sanitary conditions seemed to exist. In 1843, the "Tyler Grippe," or influenza, made its appearance. It was said to have come from Europe. The cases were ushered in by pain in the back and limbs, great muscular lassitude, chilliness, running from eyes and nose, hoarseness, cough and fever. They generally lasted only a few days, but often the system seemed to be rendered very susceptible to disease. During the following autumn many cases of typhoid fever appeared, and the type of disease seemed about this time to change from the sthenic(2) to the asthenic(3) or typhoid. Blood-letting, purging, and other depressing measures were hence largely abandoned, and a more supporting treatment introduced, which has continued to the present time. Scarlet fever again prevailed very extensively, and in a very fatal form in 1848 and 1849. If the patient survived the first stage, the eruption was profuse, the throat and adjacent parts greatly swollen and very painful, rendering deglutition almost impossible. This was often followed by sloughing off of portions of the tonsils and soft palate, usually terminating in death. In 1847-9 there prevailed about Wheeling, as well as in many parts of the country, a disease called black tongue, erysipelas, etc. Puerperal fever of a malignant type prevailed at the same time, producing many deaths. No causes could be assigned for these outbreaks. A second epidemic of cholera set in May 19, 1849, and continued until September. The cases were not nearly as numerous as in the epidemic of 1832, but many cases occurred during the two or three summers following, perhaps to 1854. Many deaths from this disease occurred among the men working on the B.& O. railroad, then in course of construction. "The narrows," about five miles below Wheeling on the river, seemed to be a choice locality for the disease, and about here many railroad laborers died. In the fall of 1857 diptheria made its appearance in Wheeling as an epidemic. The older physicians claimed to have seen the same disease in sporadic form under the name of putrid sore throat. Now, however, the cases were numerous and severe; sometimes affecting whole families, and being attended with frightful mortality. Since this endemic, diptheria has frequently visited the city, and sometimes the surrounding country. In the autumn of 1879 it prevailed to such an extent in the eastern part of the city, that a number of prominent physicians petitioned the city council for the enforcement of rigid sanitary measures against its further spread. In 1863 a few cases of cerebro-spinal meningitis, or spotted fever, occurred in the city. Some of the patients died very suddenly, after but a few hours' illness; others were sick for several days before a fatal result occurred, while a number recovered, but very slowly. Cases of this disease were seen also during 1864-5. During these years there were also very many cases of typhoid fever, pneumonia and erysipelas. In the summer of 1873 cholera made its appearance in the city. Dr. Jepson, at that time city health officer, believed that the disease was imported from Cincinnati, Ohio. During the summer thirty-five cases were officially reported to the health officer by the attending physicians. If these, twenty-two proved fatal, a mortality of sixty- three per cent. It is probable that a few unreported cases occurred, with favorable results, thus reducing the mortality. The reported cases were carefully looked after by the health officer, and all possible sanitary precautions were taken to limit the disease. During the early part of 1873, puerperal fever cases were more numerous than at any time since 1849, and they were attended with great fatality. The disease generally set in within forty-eight hours of delivery, the initial symptoms being either a distinct chill or chilly sensation. These were followed by fever, varying from 102 to 105 degrees. The pulse was quick and never strong, abdomen always distended, tenderness in pelvic region, and a tendency to delirium which was sometimes well marked. The tongue early became dry, sordes(4) appearing on the teeth, and the pulse early gave way, this typical condition speedily terminating in death. For several years there continued in the city a tendency toward puerperal diseases. In the fall of 1873 typhoid fever prevailed in Wheeling to an extent never before known. It was estimated that four or five hundred cases occurred during the last four months of the year in Wheeling alone. As a rule the cases were of a mild type and very many of them were among children. In the winter of 1874-5 scarlet fever cases were very numerous, especially in the southern end of the city. It was estimated that in the Eighth ward, with a population of about 4,000, not less than 250 cases occurred from October to April, inclusive. More of the cases were severe, many being of the anginose variety, and the others were complicated with diptheria. In the malignant cases the eruption was of a dark, purplish hue, and it was slow to recede, remaining long after its usual period. An indescribable, peculiarly fetid odor was said to exist, by which, alone, cases were sometimes diagnosed before the patient was seen. Inflammation of the cervical glands, as a sequel was quite common, and in an unusual number of cases this was followed by suppuration and sloughing of tissue. About the beginning of 1890 influenza, under the name of the Russian grippe, made its appearance in this section of the country on its westward journey from Russia, where it seems to have had its origin. It prevailed to an unheard of extent, scarcely a family escaping. The symptoms varied in different cases, sometimes the nervous system, sometimes pulmonary, and again the gastro-intestinal tract being chiefly affected. Hence some patients suffered violent pains in the head and other parts of the body, others were attacked with vomiting and purging, and still others with more or less grave pulmonary symptoms. Nearly all experienced the ordinary catarrh of nose and bronchial tubes. All cases were attended with prostration, and while as a rule the acute symptoms continued but a few days, not unfrequently pneumonia, bronchitis, or a continued fever of longer duration developed, while the prostration, especially with the aged and feeble, was great and protracted. The mortality in Wheeling during the first months of 1890, was unprecedented. Pneumonia, dysentary, measles and typhoid fever all prevailed. During February, March and April, the number of typhoid cases was very large, but the type was not severe. The deaths during the first four months were, from pneumonia, 57; typhoid fever 64. Total from all causes, in January, 77; February, 96; March, 104; April, 86. For the four months, total equal 363, which is over 31 per 1,000 of population. *For the facts here given concerning the earlier epidemics we are indebted largely to published papers of Drs. Hildreth & Frissell. (Some Definitions...) (1) erysipelas - Acute febrile disease with localized inflammation and redness of skin and subcutaneous tissue accompanied by systemic disturbance. Caused by Streptococcus pyogenes. (2) sthenic - Normal or unusual strength. (3) asthenic - Weak. (4) sordes - Foul brown crusts or accumulations on the teeth and about the lips from foul stomach or secretions of the mouth in low forms of fever.